Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714067 | 0.83 | AKR1C1 (0.59) | AKR1C1F2F10F12F7 | |
| SCHEMBL2720851 | 0.78 | NQO2 (0.47) | NQO2PTGS1PTGS2KDM1A | |
| SCHEMBL19433105 | 0.74 | PTGS1 (0.47) | NQO2PTGS1PTGS2MAPTKMT2A | |
| SCHEMBL3811778 | 0.71 | PTGS1 (0.75) | NQO2PTGS1PTGS2 | |
| SCHEMBL3811776 | 0.71 | PTGS1 (0.75) | NQO2PTGS1PTGS2 | |
| SCHEMBL5183566 | 0.71 | PTGS1 (0.49) | NQO2PTGS1PTGS2 | |
| SCHEMBL9280210 | 0.70 | AKR1C1 (0.61) | AKR1C1PTGS2MAPTKMT2AMEN1 | |
| SCHEMBL15285768 | 0.68 | NQO2 (0.51) | NQO2PTGS1PTGS2 | |
| SCHEMBL30096044 | 0.68 | NQO2 (0.61) | NQO2AKR1C1PTGS1PTGS2KMT2A | |
| SCHEMBL80025 | 0.66 | AKR1C1 (0.74) | AKR1C1PTGS2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014004339-A2 | METHOD FOR STIMULATING CELLULAR BETA DEFENSINS | ELC MANAGEMENT LLC (US) | 2014-01-03 | — | — | WO | disclosed |
| EP-2445511-A2 | SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS | ELC Management LLC (US) | 2012-05-02 | — | — | EP | disclosed |
| EP-2192889-A2 | COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN | ELC Management LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009023416-A2 | COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN | ELC MANAGEMENT LLC (US) | 2009-02-19 | — | — | WO | disclosed |