Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714067 | 0.85 | AKR1C1 (0.59) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL3296981 | 0.84 | AKR1C1 (0.74) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL80025 | 0.84 | AKR1C1 (0.74) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL23593943 | 0.81 | AKR1C1 (0.70) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2836206 | 0.81 | AKR1C1 (0.70) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6689798 | 0.81 | AKR1C1 (0.70) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL39275 | 0.76 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL290469 | 0.76 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL181529 | 0.76 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| Phosphoric Acid SCHEMBL3676597 | 0.75 | AKR1C1 (0.61) | AKR1C1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405688-A | High modulus, toughness | DOW CORNING CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5378532-A | Epoxy resin/aminofunctional polysiloxane fiber-reinforced composite | DOW CORNING CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| US-5135993-A | Phenyl-amd aminofunctional polysiloxanes | DOW CORNING CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |