Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280210 | 0.85 | AKR1C1 (0.61) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL2719795 | 0.83 | NQO2 (0.54) | AKR1C1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3296981 | 0.82 | AKR1C1 (0.74) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL80025 | 0.82 | AKR1C1 (0.74) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL23593943 | 0.79 | AKR1C1 (0.70) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL6689798 | 0.79 | AKR1C1 (0.70) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL2836206 | 0.79 | AKR1C1 (0.70) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL3654785 | 0.76 | MCL1 (0.42) | AKR1C1KMT2AALDH1A1F2F10 | |
| SCHEMBL1386540 | 0.75 | AKR1C1 (0.70) | AKR1C1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL236283 | 0.74 | MCL1 (0.48) | AKR1C1ALDH1A1F2F10F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372451-B1 | Histochemical labeling stain for myelin in brain tissue | SCHMUED LAURENCE C (US) | 2002-04-16 | — | — | US | disclosed |
| US-4716905-A | Method of retrograde fluorescent labeling of neurons | FLUOROCHROME, INC. (US) | 1988-01-05 | — | — | US | disclosed |
| US-4716905-A | Method of retrograde fluorescent labeling of neurons | FLUOROCHROME, INC. (US) | 1988-01-05 | — | — | US | disclosed |