Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296981 | 1.00 | AKR1C1 (0.74) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL18721495 | 0.87 | AKR1C1 (0.64) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL39275 | 0.85 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL290469 | 0.85 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL181529 | 0.85 | AKR1C1 (1.00) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL23069110 | 0.84 | AKR1C1 (0.73) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11219395 | 0.84 | AKR1C1 (0.73) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9280210 | 0.84 | AKR1C1 (0.61) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11219398 | 0.84 | AKR1C1 (0.73) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL10629579 | 0.84 | AKR1C1 (0.61) | AKR1C1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4195990-A | PARA-LINKED POLYPHENYLS OR POLYARYL UNSATURATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1980-04-01 | — | — | US | claimed |
| US-4105447-A | Photoconductive insulating compositions including polyaryl hydrocarbon photoconductors | EASTMAN KODAK COMPANY (US) | 1978-08-08 | — | — | US | claimed |
| US-4045220-A | ELECTROGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-08-30 | — | — | US | claimed |
| US-9618453-B2 | Aggregation induced emission of fluorescent bioprobes and methods of using the same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-04-11 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-20130079484-A1 | ORGANIC-INORGANIC HYBRID POLYMER HAVING QUANTUM WELL STRUCTURES | MOLECULAR ELECTRONICS CONSULTING (KR) | 2013-03-28 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |
| WO-2007132986-A1 | SILICON TYPE COMPOUND HAVING BISPHENYLCARBAZOL IN MOLECULE AND METHOD FOR PREPARING ORGANIC THIN LAYER OF ORGANIC LIGHT EMITTING DEVICES USING THE SAME | DONGJIN SEMICHEM CO., LTD (KR) | 2007-11-22 | — | — | WO | disclosed |
| US-20070243651-A1 | Organic EL light emitting display device and method of manufacturing the same | MIZUNO YUKITAMI | 2007-10-18 | — | — | US | disclosed |
| US-20060240565-A1 | Environment sensor and conjugated polyene for manufacturing environment sensors | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) | 2006-10-26 | — | — | US | disclosed |
| US-5652067-A | Organic electroluminescent device | TOPPAN PRINTING CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| US-4195990-A | PARA-LINKED POLYPHENYLS OR POLYARYL UNSATURATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4105447-A | Photoconductive insulating compositions including polyaryl hydrocarbon photoconductors | EASTMAN KODAK COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-4045220-A | ELECTROGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | FUS, CD63, EPCAM | AKR1C1 3610/4885MAPT 580/4885HPGD 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.