Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 5/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363477 | 1.00 | RXRA (0.32) | RXRAGSTA1GSTP1CNR1CNR2 | |
| SCHEMBL27029670 | 1.00 | RXRA (0.32) | RXRAGSTA1GSTP1CNR1CNR2 | |
| SCHEMBL27200789 | 0.95 | PPARD (0.34) | RXRAGSTA1GSTP1CNR1CNR2 | |
| SCHEMBL23363094 | 0.95 | PPARD (0.34) | RXRAGSTA1GSTP1CNR1CNR2 | |
| SCHEMBL27029681 | 0.95 | PPARD (0.34) | RXRAGSTA1GSTP1CNR1CNR2 | |
| SCHEMBL27029643 | 0.92 | DGAT1 (0.32) | RXRACNR1CNR2MAPTPPARD | |
| SCHEMBL23362013 | 0.90 | GSTA1 (0.33) | GSTA1GSTP1CNR1CNR2TP53 | |
| SCHEMBL27029650 | 0.90 | GSTA1 (0.33) | GSTA1GSTP1CNR1CNR2TP53 | |
| SCHEMBL27029722 | 0.88 | PPARD (0.40) | PPARDKDM4CPPARANQO2MTNR1A | |
| SCHEMBL27029660 | 0.86 | CNR1 (0.40) | CNR1CNR2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041734-B1 | DERIVATIVES HAVING 1,2,3,4-TETRAHYDRONAPHTHALENE MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2024-04-24 | — | — | EP | claimed |