SCHEMBL27201090

SCHEMBL27201090

CCN(C)C=Nc1cc(C)c(C(C#N)c2ccccc2)cc1C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
CYP3A4 P08684 1/20 0.31
ADRA2A P08913 1/20 0.31
MAPK1 P28482 1/20 0.31
KCNH2 Q12809 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926284 0.85 MC4R (0.37) GAA
SCHEMBL21495602 0.85 MC4R (0.37) GAA
SCHEMBL27201074 0.81 ALDH1A1 (0.35) ALDH1A1GAACYP3A4ADRA2A
SCHEMBL27201065 0.81 GAA (0.36) ALDH1A1GAACYP3A4MAPK1
SCHEMBL27201034 0.80 CYP2D6 (0.34) CYP3A4ADRA2AMAPK1KCNH2
SCHEMBL21495742 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL21495739 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL27201102 0.79 AOC3 (0.32) ALDH1A1GAA
SCHEMBL27201081 0.79 ALDH1A1 (0.35) ALDH1A1GAA
SCHEMBL28293762 0.79 ALDH1A1 (0.35) ALDH1A1GAANPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3525588-B1 4-SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE TO PROTECT CROPS BY FIGHTING UNDESIRED PHYTOPATHOGENIC MICOORGANISMS PI INDUSTRIES LTD (IN) 2024-04-24 EP claimed