SCHEMBL28293762

SCHEMBL28293762

CCN(C)C=Nc1cc(C)c(C(C#N)c2ccccc2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
CYP3A4 P08684 1/20 0.32
PDE10A Q9Y233 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
AKR1C3 P42330 1/20 0.31
AKR1C1 Q04828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27201090 0.79 ALDH1A1 (0.34) ALDH1A1GAANPC1POLBRAB9A
SCHEMBL28292069 0.73
SCHEMBL28292062 0.71 CHRM4 (0.37) ALDH1A1POLB
SCHEMBL28293867 0.70 TSHR (0.33) ALDH1A1NPC1RAB9AMAPK1SLC6A2
SCHEMBL799378 0.68 ALDH1A1 (0.38) ALDH1A1GAARAB9ACYP3A4MAPK1
SCHEMBL28293765 0.67 IDH1 (0.37) SLC6A2SLC6A4SLC6A3
SCHEMBL23926284 0.66 MC4R (0.37) GAASLC6A2SLC6A4
SCHEMBL21495602 0.66 MC4R (0.37) GAASLC6A2SLC6A4
SCHEMBL21495739 0.65 ALDH1A1 (0.33) ALDH1A1
SCHEMBL21495742 0.65 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN claimed
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN disclosed