SCHEMBL27201239

SCHEMBL27201239

Cc1cc(Cc2ccccc2Cl)c(C)cc1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.66
CYP1A2 P05177 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 1/20 0.50
CASP7 P55210 1/20 0.50
HIF1A Q16665 1/20 0.50
PNMT P11086 1/20 0.42
MPO P05164 1/20 0.41
ADCY10 Q96PN6 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CD44 P16070 1/20 0.39
CYP2C19 P33261 1/20 0.39
IDO1 P14902 3/20 0.39
PNP P00491 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20268118 0.90 ALDH1A1 (0.50) ALDH1A1CYP1A2HSD17B10PNMTMPO
SCHEMBL30290875 0.84 ALDH1A1 (0.73) ALDH1A1CYP1A2HSD17B10ALOX15CASP7
SCHEMBL941288 0.81 ALDH1A1 (1.00) ALDH1A1CYP1A2HSD17B10ALOX15CASP7
SCHEMBL27201211 0.79 ALDH1A1 (0.66) ALDH1A1CYP1A2HSD17B10ALOX15CASP7
SCHEMBL22231950 0.76 MPO (0.44) ALDH1A1PNMTMPOADCY10TAAR1
SCHEMBL22232311 0.76 PNMT (0.42) ALDH1A1CYP1A2HSD17B10PNMTMPO
SCHEMBL29454303 0.76 PNMT (0.42) ALDH1A1CYP1A2HSD17B10PNMTMPO
SCHEMBL20268128 0.76 ALDH1A1 (0.46) ALDH1A1CYP1A2MPOADCY10TAAR1
SCHEMBL20267786 0.76 ALDH1A1 (0.59) ALDH1A1CYP1A2HSD17B10ALOX15CASP7
SCHEMBL10341258 0.75 ALDH1A1 (0.64) ALDH1A1CYP1A2HSD17B10ALOX15CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3525588-B1 4-SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE TO PROTECT CROPS BY FIGHTING UNDESIRED PHYTOPATHOGENIC MICOORGANISMS PI INDUSTRIES LTD (IN) 2024-04-24 EP disclosed