Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27201549 | 0.74 | IRAK4 (0.44) | HDAC4IRAK4MAPK8NPSR1MIF | |
| SCHEMBL5762778 | 0.71 | IRAK4 (0.50) | HDAC4IRAK4MAPK8NPSR1MIF | |
| Hydrochloric Acid SCHEMBL947525 | 0.70 | IRAK4 (0.49) | HDAC4IRAK4MAPK8NPSR1MIF | |
| Hydrochloric Acid SCHEMBL26911778 | 0.70 | IRAK4 (0.49) | HDAC4IRAK4MAPK8NPSR1MIF | |
| SCHEMBL596560 | 0.68 | PRCP (0.44) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL26986647 | 0.68 | PRCP (0.44) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL25521500 | 0.67 | IRAK4 (0.45) | ADORA3HDAC4IRAK4NPSR1FLT3 | |
| SCHEMBL27201495 | 0.67 | IRAK4 (0.54) | HDAC4IRAK4MAPK8FLT3 | |
| SCHEMBL27201566 | 0.66 | IRAK4 (0.41) | IRAK4FLT3SSTR4 | |
| SCHEMBL10375118 | 0.65 | CHRNB2 (0.56) | NPSR1ALDH1A1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | GID4, MDM2, XIAP | ADORA3 4214/4885HDAC4 2313/4885IRAK4 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.