Propylene Carbonate

Propylene Carbonate

SCHEMBL2720157

CC1COC(=O)O1.CCOC(=O)C(C)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.31
LIPE Q05469 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PIN1 Q13526 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30
GLA P06280 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Carbonate SCHEMBL28444319 0.89 ATM (0.32) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL26613633 0.88 TAS1R3 (0.31) KDM4EGLA
Propylene Carbonate SCHEMBL5538622 0.84 ALDH1A1 (0.45) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL20471963 0.83 ALDH1A1 (0.36) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL28331596 0.83 ALDH1A1 (0.47) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL7170004 0.83 ALDH1A1 (0.33) ATMALDH1A1KDM4ETSHRNPSR1
Propylene Carbonate SCHEMBL25212144 0.82 GLA (0.35) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL25435165 0.81 MGAM (0.35) ATMALDH1A1KDM4ECYP2D6TSHR
Propylene Carbonate SCHEMBL27788355 0.81 ALOX15 (0.48) ATMALDH1A1KDM4ETSHRNPSR1
Propylene Carbonate SCHEMBL11425072 0.80 TP53 (0.41) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012059936-A1 PHARMACEUTICAL COMPOSITIONS FOR COLLOIDAL DRUG DELIVERY DEVARAJAN PADMA VENKITACHALAM (IN) 2012-05-10 WO disclosed