Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202080 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202096 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202078 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202089 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202102 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202083 | 0.81 | RAB9A (0.44) | ALDH1A1HSD17B10CYP1A2KDM4ECYP2C9 | |
| SCHEMBL966950 | 0.80 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TSHRHTTADRB2 | |
| SCHEMBL963334 | 0.78 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TSHRHTTKDM4E | |
| SCHEMBL1579904 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HSD17B10USP2TSHRHTR6 | |
| SCHEMBL27202084 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HSD17B10USP2TSHRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ALDH1A1 446/4885HSD17B10 1255/4885USP2 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.