Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202076 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27202075 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27202087 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27202066 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27202080 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27202055 | 0.72 | HTR6 (0.50) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL27207432 | 0.71 | ADRB1 (0.39) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL11816194 | 0.68 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL1046759 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRUSP2HTR6 | |
| SCHEMBL5707831 | 0.67 | HTR6 (0.60) | ALDH1A1HSD17B10TSHRUSP2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ALDH1A1 446/4885HSD17B10 1255/4885TSHR 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.