Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207483 | 0.86 | CYP3A4 (0.46) | ADRB1HTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27207499 | 0.85 | ADRB1 (0.44) | ADRB1HTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27207290 | 0.83 | CHRM3 (0.47) | MAPK8MAPK9MAPK10GAASMN1; SMN2 | |
| SCHEMBL27202055 | 0.79 | HTR6 (0.50) | ADRB1MAPK8MAPK9MAPK10HTR3A | |
| SCHEMBL4062286 | 0.76 | ADRB1 (0.44) | ADRB1MT-CO2HTR1ACYP1A2CYP3A4 | |
| SCHEMBL1742847 | 0.76 | ADRB1 (0.51) | ADRB1MAPK8MAPK9MAPK10HTR1A | |
| SCHEMBL6890118 | 0.73 | HTR2C (0.40) | MAPK8MAPK9MAPK10MT-CO2HTR1A | |
| SCHEMBL5745223 | 0.73 | ADRB1 (0.49) | ADRB1HTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5745278 | 0.72 | ALDH1A1 (0.53) | ADRB1HTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3951662 | 0.72 | ADRB1 (0.47) | ADRB1MT-CO2HTR1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ADRB1 4492/4885MAPK8 2927/4885MAPK9 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.