Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922736 | 0.90 | PTPN11 (0.43) | PTPN11FABP4 | |
| SCHEMBL27210353 | 0.89 | PTPN11 (0.35) | PTPN11FABP4 | |
| SCHEMBL27210388 | 0.88 | PTPN11 (0.44) | PTPN11FABP4 | |
| SCHEMBL26923548 | 0.81 | FABP4 (0.38) | FABP4 | |
| SCHEMBL29391376 | 0.80 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL22495571 | 0.80 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL29388480 | 0.70 | PTPN11 (0.58) | PTPN11 | |
| SCHEMBL21681391 | 0.70 | PTPN11 (0.58) | PTPN11 | |
| SCHEMBL22495555 | 0.70 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL29389997 | 0.70 | PTPN11 (0.48) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140931-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-05-02 | — | — | US | disclosed |
| EP-4288436-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-116940573-A | Tricyclic compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2023-10-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240140931-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | CYP2C19, CYP3A7, CYP11B2 | PTPN11 3259/4885FABP4 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.