Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.60 |
| ▸ | FLT1 | P17948 | 7/20 | 0.59 |
| ▸ | KDR | P35968 | 7/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.59 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.59 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.59 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.59 |
| ▸ | LCK | P06239 | 5/20 | 0.59 |
| ▸ | SRC | P12931 | 5/20 | 0.59 |
| ▸ | BMP4 | P12644 | 4/20 | 0.59 |
| ▸ | BMPR1B | O00238 | 4/20 | 0.59 |
| ▸ | BMPR1A | P36894 | 4/20 | 0.59 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.59 |
| ▸ | RPS6KA1 | Q15418 | 4/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21193361 | 0.76 | KDR (0.52) | TGFBR1KDRBMP4TGFBR2PIK3CD | |
| Dorsomorphin SCHEMBL463155 | 0.74 | KDR (1.00) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| SCHEMBL373363 | 0.74 | TGFBR1 (0.69) | TGFBR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| Dorsomorphin SCHEMBL2119244 | 0.73 | KDR (0.98) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| Dorsomorphin SCHEMBL17845800 | 0.73 | KDR (0.98) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| SCHEMBL15103081 | 0.73 | PRKAB2 (0.68) | TGFBR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11953875 | 0.73 | KDR (0.83) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| Dorsomorphin SCHEMBL26968137 | 0.72 | KDR (0.94) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| SCHEMBL11953876 | 0.72 | KDR (1.00) | TGFBR1FLT1KDRACVR1PRKAB2 | |
| SCHEMBL13126027 | 0.72 | KDR (0.72) | TGFBR1FLT1KDRACVR1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976296-B2 | Means and methods for generating midbrain organoids | UNIVERSITÉ DU LUXEMBOURG (LU) | 2024-05-07 | — | — | US | disclosed |
| WO-2022149616-A1 | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | 国立大学法人京都大学 | 2022-07-14 | — | — | WO | disclosed |