SCHEMBL27214226

SCHEMBL27214226

Cn1ccnc1S(=O)(=O)Nc1ccc(F)c2cccnc12

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC40A1 Q9NP59 11/20 0.62
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ TDP1 Q9NUW8 2/20 0.48
▸ GLO1 Q04760 2/20 0.47
▸ MCL1 Q07820 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ PKM P14618 1/20 0.45
▸ MMP2 P08253 1/20 0.45
▸ MMP9 P14780 1/20 0.45
▸ CKS1B P61024 1/20 0.45
▸ SKP2 Q13309 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30925523 0.85 SLC40A1 (0.59) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL27214301 0.85 SLC40A1 (0.59) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL27214169 0.85 GLO1 (0.48) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL27214304 0.80 GLO1 (0.60) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL30925442 0.80 GLO1 (0.60) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL27214240 0.79 SLC40A1 (0.62) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL30925404 0.79 SLC40A1 (0.62) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL11973361 0.77 SLC40A1 (1.00) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL30925446 0.77 SLC40A1 (0.67) SLC40A1MEN1KMT2ATDP1GLO1
SCHEMBL30925558 0.75 SLC40A1 (0.63) SLC40A1MEN1KMT2ATDP1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 SLC40A1 3357/4885MEN1 2604/4885KMT2A 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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