Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.62 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658830 | 1.00 | KDM1A (0.62) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL12714992 | 1.00 | KDM1A (0.62) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL12295868 | 0.83 | KDM1A (0.68) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL883113 | 0.83 | KDM1A (0.68) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL15606869 | 0.82 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL12875752 | 0.77 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1524305 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL17403045 | 0.77 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1524304 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL24658449 | 0.77 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150298-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2024-05-09 | — | — | US | disclosed |
| EP-4294792-A1 | ANTIBACTERIAL COMPOUNDS | Blacksmith Medicines, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| CN-117279898-A | Antibacterial compounds | 布莱克史密斯医药公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150298-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, MPO, RPN2 | KDM1A 3910/4885MAOB 1817/4885KCNH2 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.