Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | DUT | P33316 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17185826 | 1.00 | CA12 (0.42) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL25390430 | 1.00 | CA12 (0.42) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL23364467 | 1.00 | CA12 (0.42) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL23611465 | 1.00 | CA12 (0.42) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL20564496 | 0.96 | CA12 (0.44) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL20294716 | 0.93 | CA12 (0.40) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL4739003 | 0.93 | CA12 (0.40) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL19543562 | 0.89 | CA12 (0.36) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL29704301 | 0.89 | ALDH1A1 (0.38) | CA12CA1CA9DUTALDH1A1 | |
| SCHEMBL5854114 | 0.87 | CA12 (0.40) | CA12CA1CA9DUTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-03-30 | — | — | US | disclosed |
| EP-4084829-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | Oregon Health & Science University (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021138116-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
| EP-1465962-B1 | ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES | UNIV FLORIDA (US) | 2012-01-04 | — | — | EP | disclosed |
| US-6417009-B1 | COUPLING LIPID | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY INSTITUTE (AU) | 2002-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | GAP43, NTRK1, MAG | CA12 2344/4885CA1 1882/4885CA9 3156/4885 |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | CA12 2687/4885CA1 3277/4885CA9 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.