Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270669 | 0.93 | TSHR (0.32) | SCDKEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL271710 | 0.85 | ALPL (0.33) | ALDH1A1 | |
| SCHEMBL271720 | 0.83 | SCD (0.35) | SCDKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL272027 | 0.83 | KEAP1 (0.35) | SCDKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL271755 | 0.82 | MAPT (0.41) | ALDH1A1 | |
| SCHEMBL271937 | 0.82 | POLB (0.37) | SCDKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL270926 | 0.81 | ALDH1A1 (0.39) | SCDALDH1A1TSHR | |
| SCHEMBL271422 | 0.81 | TSHR (0.32) | SCDKEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL272015 | 0.80 | MRGPRX4 (0.36) | — | |
| SCHEMBL272118 | 0.79 | KEAP1 (0.35) | SCDKEAP1NFE2L2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | SCD 3715/4885KEAP1 34/4885NFE2L2 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.