Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898035 | 0.80 | HCAR2 (0.36) | HCAR2KEAP1NFE2L2TNF | |
| SCHEMBL26093310 | 0.80 | ALDH1A1 (0.39) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL26093305 | 0.80 | ALDH1A1 (0.39) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL27216580 | 0.78 | ALDH1A1 (0.47) | HCAR2KEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL30898078 | 0.72 | TSHR (0.37) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL16140874 | 0.72 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL30622827 | 0.72 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL30898063 | 0.71 | KDM1A (0.44) | HCAR2KEAP1NFE2L2TNFALDH1A1 | |
| SCHEMBL30918951 | 0.71 | SCD5 (0.39) | ALDH1A1 | |
| SCHEMBL25301 | 0.70 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2TNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4368614-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-05-15 | — | — | EP | disclosed |