Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24881235 | 0.81 | HCAR2 (0.43) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2189172 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2189175 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL28979818 | 0.79 | HCAR2 (0.41) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL27216617 | 0.78 | HCAR2 (0.35) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL24881236 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL25698382 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL7397962 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2190802 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTHCAR2KEAP1 | |
| SCHEMBL2190798 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTHCAR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4368614-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-05-15 | — | — | EP | disclosed |