Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.52 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.52 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554445 | 0.79 | MAPK14 (0.54) | RPS6KA3HTR1AHTR7HTR2BHTR6 | |
| SCHEMBL5248907 | 0.76 | RPS6KA3 (0.81) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL695032 | 0.74 | LMNA (0.53) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL12369662 | 0.74 | AKT1 (0.53) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL27217254 | 0.74 | DYRK1A (0.42) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL30639592 | 0.74 | RPS6KA3 (0.59) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL15658520 | 0.74 | RPS6KA3 (0.52) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| Bromide SCHEMBL11756541 | 0.74 | RPS6KA3 (0.79) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL28815310 | 0.74 | RPS6KA3 (0.52) | RPS6KA3AKT1FGFR1GSK3BAURKA | |
| SCHEMBL30919457 | 0.72 | TGFBR1 (0.60) | TGFBR1LMNAKDM4EMAPK14CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584259-A1 | CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS | Innovo Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119019332-A | 1, 5-Disubstituted-4-bromopyrazole compound and preparation method and application thereof | 赣南师范大学 | 2024-11-26 | — | — | CN | disclosed |
| US-20240158370-A1 | CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. | 2024-05-16 | — | — | US | disclosed |
| WO-2024054832-A1 | CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158370-A1 | CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS | CKS1B, CKS2, MARK1 | RPS6KA3 1475/4885AKT1 3020/4885FGFR1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.