Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.81 |
| ▸ | AKT1 | P31749 | 2/20 | 0.81 |
| ▸ | AURKA | O14965 | 1/20 | 0.81 |
| ▸ | CDK1 | P06493 | 1/20 | 0.81 |
| ▸ | LYN | P07948 | 1/20 | 0.81 |
| ▸ | PIM1 | P11309 | 1/20 | 0.81 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.81 |
| ▸ | PRKACA | P17612 | 1/20 | 0.81 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.81 |
| ▸ | CDK2 | P24941 | 1/20 | 0.81 |
| ▸ | MARK3 | P27448 | 1/20 | 0.81 |
| ▸ | GSK3B | P49841 | 1/20 | 0.81 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.81 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.81 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.81 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.81 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.81 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.81 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.65 |
| ▸ | AKT2 | P31751 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11756541 | 0.98 | RPS6KA3 (0.79) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL6076343 | 0.90 | RPS6KA3 (1.00) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL6073381 | 0.90 | RPS6KA3 (1.00) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL6132062 | 0.89 | RPS6KA3 (0.70) | RPS6KA3AKT1AURKACDK1LYN | |
| Propionic Acid SCHEMBL10557736 | 0.84 | RPS6KA3 (0.64) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL6132035 | 0.82 | TGFBR1 (0.61) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL14577335 | 0.80 | MAPK1 (0.61) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL30204300 | 0.77 | MEN1 (0.73) | RPS6KA3LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL27540520 | 0.77 | RPS6KA3 (0.57) | RPS6KA3AKT1AURKACDK1LYN | |
| SCHEMBL22671965 | 0.77 | MEN1 (0.73) | RPS6KA3LMNAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180203175-A1 | TRIAZOLE COMPOUND | Konica Minolta, Inc. (JP) | 2018-07-19 | — | — | US | disclosed |
| US-10012777-B2 | Resin composition | Konica Minolta, Inc. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | KONICA MINOLTA, INC (JP) | 2015-11-26 | — | — | US | disclosed |
| EP-1542680-B1 | 1, 4, 5-SUBSTITUTED 1, 2-DIHYDRO-PYRAZOL-3-ONE AND 3-ALKOXY-1H-PYRAZOLE DERIVATIVES AS TNF-ALPHA AND INTERLEUKIN LOWERING AGENTS FOR THE TREATMENT OF INFLAMMATIONS | AMGEN INC (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-0417449-B1 | Arylpyrazole derivatives as platelet aggregation inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5071866-A | Arylpyrazole derivatives as anti-platelet agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994482-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0299407-B1 | 1H-PYRAZOLE-1-ALKANAMIDES AND PREPARATION USEFUL AS ANTIARRHYTHMIC AGENTS | STERLING DRUG INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0388690-A1 | Azole-1-alkanamides as antiarrhytmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4870095-A | 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use | STERLING DRUG, INC. (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0299407-A1 | 1H-pyrazole-1-alkanamides and preparation useful as antiarrhythmic agents | STERLING DRUG INC. (US) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | HRH3, HELZ, NBAS | RPS6KA3 3170/4885AKT1 776/4885AURKA 2167/4885 |
| US-10012777-B2 | Resin composition | NBAS, WDR5, HRH3 | RPS6KA3 3329/4885AKT1 1375/4885AURKA 2986/4885 |
| US-20180203175-A1 | TRIAZOLE COMPOUND | H1-10, TTI2, H1-2 | RPS6KA3 3549/4885AKT1 3686/4885AURKA 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.