Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415897 | 0.86 | LMNA (0.71) | LMNASMN1; SMN2HTTTGM2CA12 | |
| SCHEMBL13055383 | 0.85 | LMNA (0.80) | LMNASMN1; SMN2HTTTGM2CA12 | |
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.83 | PLAU (0.70) | LMNASMN1; SMN2HTTTGM2CA12 | |
| SCHEMBL250620 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2CA12 | |
| SCHEMBL8197237 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2CA12 | |
| SCHEMBL646561 | 0.83 | HTT (0.72) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL19477991 | 0.82 | LMNA (0.66) | LMNASMN1; SMN2HTTTGM2CA12 | |
| SCHEMBL4910834 | 0.82 | MGLL (0.52) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL2295789 | 0.82 | CA12 (0.66) | LMNASMN1; SMN2HTTCA12CA1 | |
| SCHEMBL3728729 | 0.82 | HTT (0.70) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998621-B2 | Transparent, fracture-tough polymerization resins for the production of dental shaped bodies | IVOCLAR VIVADENT AG (LI) | 2024-06-04 | — | — | US | claimed |
| CN-115300400-A | Transparent, fracture-tough polymeric resins for the production of dental molded bodies | 义获嘉伟瓦登特公司 | 2022-11-08 | — | — | CN | claimed |
| EP-3050883-B1 | PRODUCTION METHOD FOR DIAZABICYCLOOCTANE DERIVATIVES AND INTERMEDIATES | MEIJI SEIKA PHARMA CO LTD (JP) | 2020-04-22 | — | — | EP | claimed |
| US-10000491-B2 | Process for producing diazabicyclooctane derivative and intermediate thereof | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-06-19 | — | — | US | claimed |
| CN-105555787-B | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | 明治制果药业株式会社 | 2017-08-08 | — | — | CN | claimed |
| US-20160264573-A1 | PROCESS FOR PRODUCING DIAZABICYCLOOCTANE DERIVATIVE AND INTERMEDIATE THEREOF | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-09-15 | — | — | US | claimed |
| EP-3050883-A1 | PRODUCTION METHOD FOR DIAZABICYCLOOCTANE DERIVATIVE AND INTERMEDIARY BODY THEREOF | Meiji Seika Pharma Co., Ltd. (JP) | 2016-08-03 | — | — | EP | claimed |
| CN-105555787-A | Process for preparation of diazabicyclooctane derivatives and intermediates therefor | MEIJI SEIKA PHARMA CO LT | 2016-05-04 | — | — | CN | claimed |
| JP-4664597-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| EP-1511734-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2010-06-23 | — | — | EP | claimed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | claimed |
| EP-0329013-A2 | Renin-inhibiting amino acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | claimed |
| EP-0047079-B1 | NONAPEPTIDES AFFECTING GONADAL FUNCTION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1984-02-22 | — | — | EP | claimed |
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | claimed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | claimed |
| EP-0005348-B1 | CARBAPENEM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | claimed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | claimed |
| US-4278686-A | ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1981-07-14 | — | — | US | claimed |
| EP-0005348-A1 | Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-11-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11998621-B2 | Transparent, fracture-tough polymerization resins for the production of dental shaped bodies | MMAB, VCL, BOLA2; BOLA2B | LMNA 1795/4885SMN1; SMN2 3002/4885HTT 847/4885 |
| US-20160264573-A1 | PROCESS FOR PRODUCING DIAZABICYCLOOCTANE DERIVATIVE AND INTERMEDIATE THEREOF | CLCN2, ODC1, KCNN4 | LMNA 921/4885SMN1; SMN2 4784/4885HTT 2820/4885 |
| US-10000491-B2 | Process for producing diazabicyclooctane derivative and intermediate thereof | CLCN2, ODC1, KCNN4 | LMNA 921/4885SMN1; SMN2 4784/4885HTT 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.