SCHEMBL27220137

SCHEMBL27220137

O=Cc1ccc(OC(=O)C=Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 1.00
SMN1; SMN2 Q16637 2/20 0.52
PPARG P37231 1/20 0.51
MAPT P10636 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
MAOB P27338 2/20 0.50
MAOA P21397 1/20 0.50
HDAC3 O15379 1/20 0.50
TNKS O95271 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21791873 1.00 KMT2A (1.00) KMT2ASMN1; SMN2PPARGMAPTALDH1A1
SCHEMBL16982630 0.91 KMT2A (0.83) KMT2ASMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL28903591 0.88 KMT2A (0.78) KMT2ASMN1; SMN2MAPTALDH1A1LMNA
Phenyl Cinnamate SCHEMBL1055161 0.87 KMT2A (0.77) KMT2ASMN1; SMN2MAPTALDH1A1LMNA
Phenyl Cinnamate SCHEMBL1055160 0.87 KMT2A (0.77) KMT2ASMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL14580218 0.87 KMT2A (0.77) KMT2ASMN1; SMN2MAPTALDH1A1CYP2D6
SCHEMBL27541700 0.86 KMT2A (0.75) KMT2ASMN1; SMN2PPARGMAPTALDH1A1
SCHEMBL8936562 0.85 KMT2A (0.74) KMT2ASMN1; SMN2PPARGMAPTALDH1A1
SCHEMBL8756097 0.85 KMT2A (0.73) KMT2ASMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL8756092 0.85 KMT2A (0.73) KMT2ASMN1; SMN2MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987551-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. 2024-05-21 US claimed
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2022-07-28 US claimed
US-12637409-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. (US) 2026-05-26 US disclosed
US-20240317670-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2024-09-26 US disclosed
US-20240300883-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2024-09-12 US disclosed
US-11987551-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. 2024-05-21 US disclosed
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2022-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES ACACB, ACACA, FABP7 KMT2A 1056/4885SMN1; SMN2 2759/4885PPARG 178/4885
US-20240300883-A1 STYRYL CARBOXYLATE DERIVATIVES SCD, ACACB, ACACA KMT2A 780/4885SMN1; SMN2 3684/4885PPARG 148/4885
US-20240317670-A1 STYRYL CARBOXYLATE DERIVATIVES ACACB, ACACA, GPR119 KMT2A 995/4885SMN1; SMN2 2950/4885PPARG 151/4885
US-12637409-B2 Styryl carboxylate derivatives GPR119, ACACB, ACACA KMT2A 778/4885SMN1; SMN2 2149/4885PPARG 276/4885
US-11987551-B2 Styryl carboxylate derivatives ACACB, ACACA, FABP7 KMT2A 1056/4885SMN1; SMN2 2759/4885PPARG 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.