Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27220281 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220303 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220398 | 0.89 | KMT2A (0.57) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220275 | 0.89 | KMT2A (0.57) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220418 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220135 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220167 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220412 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220410 | 0.88 | KMT2A (0.52) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 | |
| SCHEMBL27220159 | 0.88 | KMT2A (0.52) | SMN1; SMN2KMT2AALDH1A1NFKB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220234987-A1 | STYRYL CARBOXYLATE DERIVATIVES | Renovel Innovations, Inc. | 2022-07-28 | — | — | US | claimed |
| US-12637409-B2 | Styryl carboxylate derivatives | Renovel Innovations, Inc. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20240317670-A1 | STYRYL CARBOXYLATE DERIVATIVES | Renovel Innovations, Inc. | 2024-09-26 | — | — | US | disclosed |
| US-20240300883-A1 | STYRYL CARBOXYLATE DERIVATIVES | Renovel Innovations, Inc. | 2024-09-12 | — | — | US | disclosed |
| US-11987551-B2 | Styryl carboxylate derivatives | Renovel Innovations, Inc. | 2024-05-21 | — | — | US | disclosed |
| US-20220234987-A1 | STYRYL CARBOXYLATE DERIVATIVES | Renovel Innovations, Inc. | 2022-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220234987-A1 | STYRYL CARBOXYLATE DERIVATIVES | ACACB, ACACA, FABP7 | SMN1; SMN2 2759/4885KMT2A 1056/4885ALDH1A1 313/4885 |
| US-20240300883-A1 | STYRYL CARBOXYLATE DERIVATIVES | SCD, ACACB, ACACA | SMN1; SMN2 3684/4885KMT2A 780/4885ALDH1A1 369/4885 |
| US-20240317670-A1 | STYRYL CARBOXYLATE DERIVATIVES | ACACB, ACACA, GPR119 | SMN1; SMN2 2950/4885KMT2A 995/4885ALDH1A1 349/4885 |
| US-12637409-B2 | Styryl carboxylate derivatives | GPR119, ACACB, ACACA | SMN1; SMN2 2149/4885KMT2A 778/4885ALDH1A1 683/4885 |
| US-11987551-B2 | Styryl carboxylate derivatives | ACACB, ACACA, FABP7 | SMN1; SMN2 2759/4885KMT2A 1056/4885ALDH1A1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.