Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27220884 | 1.00 | TLR7 (0.37) | TLR7KCNH2HRH4HRH3GPR84 | |
| SCHEMBL27220889 | 1.00 | TLR7 (0.37) | TLR7KCNH2HRH4HRH3GPR84 | |
| SCHEMBL27220914 | 0.98 | TLR7 (0.35) | TLR7KCNH2HRH4HRH3GPR84 | |
| SCHEMBL27220827 | 0.94 | ALDH1A1 (0.34) | TLR7HRH3HSD11B1ALDH1A1POLB | |
| SCHEMBL27220916 | 0.91 | ALDH1A1 (0.31) | TLR7HRH4HRH3ALDH1A1POLB | |
| SCHEMBL27220869 | 0.91 | TBXAS1 (0.31) | HRH4HRH3TBXAS1 | |
| SCHEMBL27839146 | 0.87 | TLR7 (0.45) | TLR7KCNH2HRH4HRH3GPR84 | |
| SCHEMBL27220906 | 0.86 | KCNH2 (0.40) | KCNH2HRH4HRH3OPRM1DRD3 | |
| SCHEMBL1461161 | 0.84 | HSD11B1 (0.41) | TLR7HRH3GPR84HSD11B1TBXAS1 | |
| SCHEMBL27220860 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481878-B1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-05-22 | — | — | EP | claimed |