Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15096081 | 0.92 | PRMT5 (0.52) | DRD4L3MBTL1DRD2DRD3PRMT5 | |
| SCHEMBL2719889 | 0.84 | MEN1 (0.41) | DRD4PRMT5WDR77LMNACYP2D6 | |
| SCHEMBL11400908 | 0.82 | LMNA (0.61) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL23589323 | 0.81 | TDP1 (0.60) | DRD4L3MBTL1DRD2DRD3KDM4E | |
| SCHEMBL267463 | 0.80 | LMNA (0.68) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL25688271 | 0.79 | LMNA (0.57) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL11959217 | 0.76 | LMNA (0.58) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL5087030 | 0.76 | LMNA (0.53) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL23135358 | 0.76 | LMNA (0.53) | L3MBTL1KDM4ELMNACYP2D6ADRB1 | |
| SCHEMBL11957610 | 0.76 | POLB (0.48) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670375-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-05-01 | — | — | EP | disclosed |
| US-9295617-B2 | Dental composition, method of producing and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-9295617-B2 | Dental composition, method of producing and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2481390-A1 | Dental composition, method of producing and use thereof | 3M Innovative Properties Company (US) | 2012-08-01 | — | — | EP | disclosed |
| WO-2012003136-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| EP-2401998-A1 | Dental composition, kit of parts and use thereof | 3M Innovative Properties Company (US) | 2012-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | PAM, PTMS, ACR | DRD4 2660/4885L3MBTL1 3828/4885DRD2 2664/4885 |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | DRD4 3106/4885L3MBTL1 3955/4885DRD2 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.