Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 6/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896236 | 0.90 | MERTK (0.56) | MERTKNPY5RCCR4PAK4CAMK2D | |
| SCHEMBL30896205 | 0.90 | MERTK (0.56) | MERTKNPY5RCCR4CAMK2DTOP2A | |
| SCHEMBL27223397 | 0.90 | MERTK (0.56) | MERTKNPY5RCCR4PAK4CAMK2D | |
| SCHEMBL27224039 | 0.90 | MERTK (0.56) | MERTKNPY5RCCR4CAMK2DTOP2A | |
| SCHEMBL27223952 | 0.89 | MERTK (0.55) | MERTKNPY5RCCR4CAMK2DTOP2A | |
| SCHEMBL27223955 | 0.88 | MERTK (0.54) | MERTKNPY5RCCR4CAMK2D | |
| SCHEMBL24649804 | 0.88 | MERTK (0.75) | MERTKNPY5RCAMK2DSOS1 | |
| SCHEMBL30896206 | 0.88 | MERTK (0.75) | MERTKNPY5RCAMK2DSOS1 | |
| SCHEMBL30896197 | 0.80 | PAK4 (0.56) | MERTKPAK4CAMK2DSOS1 | |
| SCHEMBL27223450 | 0.80 | PAK4 (0.56) | MERTKPAK4CAMK2DSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | MERTK 3423/4885NPY5R 2011/4885HTR2A 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.