Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 5/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223397 | 1.00 | MERTK (0.56) | MERTKCAMK2DAURKADAPK3JAK2 | |
| SCHEMBL27223370 | 0.90 | MERTK (0.64) | MERTKCAMK2DJAK2PAK4SOS1 | |
| SCHEMBL27223450 | 0.89 | PAK4 (0.56) | MERTKCAMK2DPAK4SOS1 | |
| SCHEMBL30896197 | 0.89 | PAK4 (0.56) | MERTKCAMK2DPAK4SOS1 | |
| SCHEMBL27224039 | 0.89 | MERTK (0.56) | MERTKCAMK2DADORA3ADORA2ASOS1 | |
| SCHEMBL30896205 | 0.89 | MERTK (0.56) | MERTKCAMK2DADORA3ADORA2ASOS1 | |
| SCHEMBL27223952 | 0.88 | MERTK (0.55) | MERTKCAMK2DADORA3ADORA2ASOS1 | |
| SCHEMBL30896255 | 0.88 | CAMK2D (0.49) | MERTKCAMK2DPAK4NTRK1SOS1 | |
| SCHEMBL27224032 | 0.88 | CAMK2D (0.49) | MERTKCAMK2DPAK4NTRK1SOS1 | |
| SCHEMBL27223955 | 0.87 | MERTK (0.54) | MERTKCAMK2DNPY5RCCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | MERTK 3423/4885CAMK2D 389/4885AURKA 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.