Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677455 | 0.76 | GAA (0.46) | KDM4EMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9724182 | 0.75 | KDM4E (1.00) | KDM4ECRHBPCRHR2MEN1ALDH1A1 | |
| SCHEMBL2721897 | 0.73 | KDM4E (0.38) | KDM4ECRHBPCRHR2ARMEN1 | |
| SCHEMBL14805753 | 0.72 | KDM4E (0.62) | KDM4ECRHBPCRHR2ARMEN1 | |
| SCHEMBL14820276 | 0.71 | KDM4E (0.66) | KDM4ECRHBPCRHR2MEN1ALDH1A1 | |
| SCHEMBL2720510 | 0.70 | HSD17B10 (0.46) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9179305 | 0.70 | KDM4E (1.00) | KDM4ECRHBPCRHR2MEN1ALDH1A1 | |
| SCHEMBL29976744 | 0.70 | KDM4E (1.00) | KDM4ECRHBPCRHR2MEN1ALDH1A1 | |
| SCHEMBL1771566 | 0.68 | AR (0.62) | AR | |
| SCHEMBL13969591 | 0.68 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364951-B1 | Triazoquinolone derivatives as pest controllers | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-7144843-B2 | Pest controllers | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-12-05 | — | — | US | disclosed |
| US-20040067852-A1 | Pest controllers | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1364951-A1 | PEST CONTROLLERS | Meiji Seika Kaisha, Ltd. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067852-A1 | Pest controllers | RER1, MSL1, SMG1 | KDM4E 1492/4885CRHBP 1988/4885CRHR2 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.