SCHEMBL2720510

SCHEMBL2720510

CCC(C)c1ccc2[nH]c(C)c(C)c(=O)c2c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 4/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ KDM4E B2RXH2 4/20 0.44
▸ GAA P10253 2/20 0.44
▸ MAPT P10636 1/20 0.40
▸ HCRTR1 O43613 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.39
▸ HPGD P15428 5/20 0.39
▸ HDAC4 P56524 1/20 0.38
▸ HDAC2 Q92769 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ PKM P14618 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ SCN10A Q9Y5Y9 1/20 0.36
▸ APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21677455 0.79 GAA (0.46) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL16622748 0.76 POLB (0.56) HSD17B10SMN1; SMN2KDM4EMAPTALDH1A1
SCHEMBL9724156 0.74 HSD17B10 (0.65) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL10063356 0.73 KDM4E (0.47) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL13969591 0.71 ALDH1A1 (0.48) HSD17B10SMN1; SMN2GAAMAPTALDH1A1
SCHEMBL8127718 0.71 KDM4E (0.57) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL17249528 0.71 KDM4E (0.56) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL2722372 0.70 KDM4E (0.59) HSD17B10SMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL10063355 0.70 MAPT (0.46) HSD17B10SMN1; SMN2KDM4EGAAMAPT
SCHEMBL20077509 0.69 HTR1D (0.44) HSD17B10GAAMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364951-B1 Triazoquinolone derivatives as pest controllers MEIJI SEIKA PHARMA CO LTD (JP) 2012-05-02 — — EP disclosed
EP-1364951-B1 Triazoquinolone derivatives as pest controllers MEIJI SEIKA PHARMA CO LTD (JP) 2012-05-02 — — EP disclosed
US-7144843-B2 Pest controllers MEIJI SEIKA KAISHA, LTD. (JP) 2006-12-05 — — US disclosed
US-20040067852-A1 Pest controllers MEIJI SEIKA KAISHA, LTD. (JP) 2004-04-08 — — US disclosed
EP-1364951-A1 PEST CONTROLLERS Meiji Seika Kaisha, Ltd. (JP) 2003-11-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067852-A1 Pest controllers RER1, MSL1, SMG1 HSD17B10 3217/4885SMN1; SMN2 653/4885KDM4E 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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