Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CTSV | O60911 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751415 | 0.87 | KMT2A (0.62) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL11091089 | 0.85 | CTSV (0.57) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL5299658 | 0.85 | ABCB1 (0.55) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL965943 | 0.84 | ALDH1A1 (0.63) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL29368594 | 0.84 | ALDH1A1 (0.63) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL750245 | 0.84 | CTSV (0.63) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL16005076 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL21775128 | 0.82 | SMN1; SMN2 (0.65) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL750963 | 0.82 | CTSV (0.58) | MAPTMEN1KMT2AABCB1CTSV | |
| SCHEMBL16004968 | 0.82 | ABCB1 (0.59) | MAPTMEN1KMT2AABCB1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053768-A2 | ARYLOXYPHENOXYACETYL-BASED COMPOUND HAVING HIF-1 INHIBITION ACTIVITY, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-26 | — | — | WO | disclosed |