Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924650 | 1.00 | MAOB (0.48) | MAOBMAOANR4A2PARP10NPC1 | |
| SCHEMBL30924578 | 0.89 | L3MBTL1 (0.47) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL27229599 | 0.89 | L3MBTL1 (0.47) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL27229575 | 0.88 | HRH3 (0.57) | NPC1RAB9ASMN1; SMN2POLBGFER | |
| SCHEMBL30924689 | 0.88 | HRH3 (0.57) | NPC1RAB9ASMN1; SMN2POLBGFER | |
| SCHEMBL29097908 | 0.87 | NR4A2 (0.53) | MAOBMAOANR4A2PARP10NPC1 | |
| SCHEMBL27229659 | 0.87 | MAPT (0.49) | MAOBNR4A2SMN1; SMN2POLBMRGPRX4 | |
| SCHEMBL30924666 | 0.87 | MAPT (0.49) | MAOBNR4A2SMN1; SMN2POLBMRGPRX4 | |
| SCHEMBL30924664 | 0.87 | MAOA (0.45) | MAOBMAOANPC1RAB9A | |
| SCHEMBL27229673 | 0.87 | MAOA (0.45) | MAOBMAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174659-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174659-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | YAP1, YES1, LATS1 | MAOB 3068/4885MAOA 3702/4885NR4A2 3575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.