Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722981 | 0.81 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL453358 | 0.79 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28190659 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ammonia Solution, Strong SCHEMBL28082936 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27442768 | 0.77 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9169902 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28082930 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28082825 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28082964 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL952090 | 0.77 | TSHR (0.38) | TSHRALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102432781-A | Cross-linkable surface fluorine-containing nano-microsphere and preparation method and application thereof | CAS GUANGZHOU CHEMISTRY CO LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-101328273-A | Water dispersible magnetic high polymer microsphere and preparation thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2008-12-24 | — | — | CN | disclosed |
| EP-0162306-B1 | IMPROVED DUNNAGE MATERIAL | THE DOW CHEMICAL COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0162306-A2 | Improved dunnage material | THE DOW CHEMICAL COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |