SCHEMBL9169902

SCHEMBL9169902

C=CC(=O)OC(=O)C(C)S

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.48
HPGD P15428 1/20 0.38
ALDH1A1 P00352 6/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28082776 0.98 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2722981 0.81 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL453358 0.79 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082964 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL28082936 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082825 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28190659 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9806301 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082930 0.77 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27442768 0.77 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US claimed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US disclosed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP disclosed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US disclosed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US disclosed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP disclosed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US disclosed
US-4778869-A COATINGS, ADHESIVES, MOLDINGS AMERICAN CYANAMID COMPANY (US) 1988-10-18 US disclosed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US disclosed
EP-0020000-B1 ACTIVATED ESTER MONOMERS, POLYMERS FORMED THEREFROM AND COATING COMPOSITIONS CONTAINING SAID POLYMERS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP disclosed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed