Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723363 | 0.80 | TGM2 (0.42) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL12799134 | 0.77 | TGM2 (0.46) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL2724245 | 0.77 | ALDH1A1 (0.38) | LMNAEGFRACP1HPGDKMT2A | |
| SCHEMBL18763028 | 0.75 | TGM2 (0.43) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL26026744 | 0.74 | TGM2 (0.48) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL25294152 | 0.74 | TGM2 (0.46) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL1022819 | 0.73 | ALDH1A1 (0.55) | TGM2LMNAMAOAMAOBHPGD | |
| SCHEMBL11179193 | 0.73 | TGM2 (0.53) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL27780299 | 0.72 | TGM2 (0.52) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL15348740 | 0.70 | LMNA (0.45) | TGM2LMNAF13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | claimed |
| US-10023782-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170335162-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | HERCULES LLC | 2017-11-23 | — | — | US | disclosed |
| US-9611416-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20130324443-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |