Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 10/20 | 0.34 |
| ▸ | MMP9 | P14780 | 10/20 | 0.34 |
| ▸ | MMP8 | P22894 | 4/20 | 0.34 |
| ▸ | MMP12 | P39900 | 4/20 | 0.34 |
| ▸ | MMP14 | P50281 | 4/20 | 0.34 |
| ▸ | BMP1 | P13497 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998756 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BL3MBTL1MMP2MMP9 | |
| SCHEMBL6877985 | 0.75 | ITGAV (0.57) | ITGB3ITGA2BL3MBTL1MMP2MMP9 | |
| SCHEMBL8492995 | 0.75 | ITGAV (0.57) | ITGB3ITGA2BL3MBTL1MMP2MMP9 | |
| SCHEMBL7262680 | 0.74 | ITGB3 (0.45) | ITGB3ITGA2BL3MBTL1MMP2MMP9 | |
| SCHEMBL1509767 | 0.73 | ITGB3 (0.71) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL1509766 | 0.73 | ITGB3 (0.71) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL9293208 | 0.73 | ITGB3 (0.71) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL28235262 | 0.73 | ITGB3 (0.43) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL7420368 | 0.72 | SLC1A3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7420373 | 0.72 | SLC1A3 (0.53) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173309-A1 | LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240173309-A1 | LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | IL23R, IL1RN, IL36G | ITGB3 1798/4885ITGA2B 4006/4885L3MBTL1 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.