Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 5/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 8/20 | 0.45 |
| ▸ | MMP9 | P14780 | 8/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 3/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877985 | 1.00 | ITGAV (0.57) | ITGAVITGB3ITGA2L3MBTL1ITGA2B | |
| SCHEMBL8013936 | 0.92 | ITGAV (0.49) | ITGAVITGB3ITGA2L3MBTL1ITGA2B | |
| SCHEMBL27412426 | 0.89 | RECQL (0.47) | ITGAVITGB3ITGA2L3MBTL1ITGA2B | |
| SCHEMBL1700935 | 0.89 | RECQL (0.47) | ITGAVITGB3ITGA2L3MBTL1ITGA2B | |
| SCHEMBL7420368 | 0.85 | SLC1A3 (0.53) | ITGAVITGB3ITGA2BSLC1A3SLC1A2 | |
| SCHEMBL8998756 | 0.85 | ITGB3 (0.49) | ITGAVITGB3L3MBTL1ITGA2BMMP2 | |
| SCHEMBL7420373 | 0.85 | SLC1A3 (0.53) | ITGAVITGB3ITGA2BSLC1A3SLC1A2 | |
| SCHEMBL3448321 | 0.84 | MMP9 (0.58) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL3448325 | 0.84 | MMP9 (0.58) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL457771 | 0.82 | MMP9 (0.65) | ITGAVITGB3ITGA2L3MBTL1ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999050229-A1 | FATTY ACID ANALOGS AND PRODRUGS | G.D. SEARLE & CO. (US) | 1999-10-07 | — | — | WO | disclosed |