Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OAT | P04181 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23299694 | 1.00 | OAT (0.46) | OATABATGABRR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL23274780 | 0.98 | OAT (0.44) | OATABATGABRR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL23274778 | 0.98 | OAT (0.44) | OATABATGABRR1TSHRMAPK1 | |
| SCHEMBL23299700 | 0.82 | OAT (0.43) | OATABATGABRR1TSHRMAPK1 | |
| SCHEMBL23299698 | 0.82 | OAT (0.43) | OATABATGABRR1TSHRMAPK1 | |
| SCHEMBL27231957 | 0.81 | ABAT (0.42) | OATABATGABRR1TSHRMAPK1 | |
| SCHEMBL27224967 | 0.81 | ABAT (0.42) | OATABATGABRR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL27224962 | 0.79 | ABAT (0.41) | OATABATGABRR1TSHRMAPK1 | |
| SCHEMBL24731262 | 0.66 | GABRP (0.33) | OATGABRR1TSHRBLMSRD5A2 | |
| SCHEMBL30782573 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174596-A1 | (S)-3-AMINO-4,4-DIHALOCYCLOPENT-1-ENECARBOXYLIC ACID AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY | 2024-05-30 | — | — | US | disclosed |
| CN-117321025-A | (S) -3-amino-4, 4-dihalocyclopent-1-enecarboxylic acid as selective inactivating agent for human ornithine aminotransferase | 西北大学 | 2023-12-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174596-A1 | (S)-3-AMINO-4,4-DIHALOCYCLOPENT-1-ENECARBOXYLIC ACID AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE | OAT, DLAT, ODC1 | OAT 1/4885ABAT 7/4885GABRR1 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.