Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233621 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL27233569 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL27164915 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL27234544 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL27233628 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL27233653 | 0.90 | KDM1A (0.54) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL30500384 | 0.85 | NPC1 (0.67) | SMN1; SMN2NPSR1EPHX2RAB9AALDH1A1 | |
| SCHEMBL12483547 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2NPSR1EPHX2RAB9AKDM1A | |
| SCHEMBL23351144 | 0.80 | ALDH1A1 (0.57) | RAB9AALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL8205762 | 0.79 | ACHE (0.59) | SMN1; SMN2NPSR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | NEUROPN THERAPEUTICS (US) | 2024-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, HPGDS | SMN1; SMN2 3266/4885NPSR1 3272/4885EPHX2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.