Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 7/20 | 0.35 |
| ▸ | BRAF | P15056 | 6/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27234162 | 1.00 | P2RX3 (0.37) | P2RX3SCN9AKDRBRAFMAPK14 | |
| SCHEMBL30212469 | 0.90 | BTK (0.38) | P2RX3SCN9AKDRBRAFRAF1 | |
| SCHEMBL27234150 | 0.88 | LNPEP (0.38) | SCN9AKDRBRAFRAF1EPHX2 | |
| SCHEMBL27234148 | 0.88 | LNPEP (0.38) | SCN9AKDRBRAFRAF1EPHX2 | |
| SCHEMBL27234126 | 0.87 | KCNQ3 (0.33) | SCN9AEPHX2 | |
| SCHEMBL27234130 | 0.87 | KCNQ3 (0.33) | SCN9AEPHX2 | |
| SCHEMBL27234117 | 0.85 | ACACB (0.34) | SCN9AKDRBRAFRAF1EPHX2 | |
| SCHEMBL27234113 | 0.85 | ACACB (0.34) | SCN9AKDRBRAFRAF1EPHX2 | |
| SCHEMBL27234111 | 0.82 | XDH (0.35) | SCN9AEPHX2 | |
| SCHEMBL27234115 | 0.82 | XDH (0.35) | SCN9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378936-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-06-05 | — | — | EP | disclosed |