Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182725 | 0.87 | LMNA (0.43) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL2721524 | 0.81 | LMNA (0.39) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL182802 | 0.72 | CYP1A2 (0.39) | ALDH1A1HTTPOLBCYP1A2 | |
| SCHEMBL182724 | 0.69 | LMNA (0.40) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL182763 | 0.68 | TDP1 (0.37) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL182721 | 0.66 | LMNA (0.43) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL183021 | 0.65 | TDP1 (0.34) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10745642 | 0.64 | CYP1A2 (0.36) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL2935528 | 0.61 | KMT2A (0.38) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL22748454 | 0.60 | NPSR1 (0.38) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465962-B1 | ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES | UNIV FLORIDA (US) | 2012-01-04 | — | — | EP | disclosed |