SCHEMBL182724

SCHEMBL182724

CCCCCCCCC1COOc2c(C(=O)OCC)[nH]c(C(=O)OCC)c2C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 7/20 0.39
HTT P42858 3/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 6/20 0.34
TSHR P16473 5/20 0.34
POLB P06746 4/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
BRD4 O60885 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 3/20 0.33
CYP2C9 P11712 2/20 0.33
PKM P14618 2/20 0.32
GAA P10253 2/20 0.32
RAB9A P51151 2/20 0.32
CREBBP Q92793 1/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182801 0.84 CYP1A2 (0.36) ALDH1A1HTTL3MBTL1CYP1A2CYP2C19
SCHEMBL182762 0.82 TDP1 (0.33) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL182725 0.80 LMNA (0.43) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL182727 0.78 CTDSP1 (0.32) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL183020 0.74 CTDSP1 (0.32) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL182720 0.73 LMNA (0.40) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL2721524 0.73 LMNA (0.39) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL182907 0.72 ALDH1A1 (0.39) LMNASMN1; SMN2MAPK1ALDH1A1HTT
SCHEMBL2723482 0.69 LMNA (0.36) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1
SCHEMBL182721 0.65 LMNA (0.43) LMNASMN1; SMN2NPSR1MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465962-B1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIV FLORIDA (US) 2012-01-04 EP disclosed
EP-1465962-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2004-10-13 EP disclosed
US-6791738-B2 CONTROLLING COLOR, BRIGHTNESS AND ENVIRONMENTAL STABILITY; POLY- 3,4-ALKYLENEDIOXYHETEROCYCLES UNIVERSITY OF FLORIDA 2004-09-14 US disclosed
US-20030174377-A1 Electrochromic polymers and polymer electrochromic devices UNIVERSITY OF FLORIDA 2003-09-18 US disclosed
WO-2003046106-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2003-06-05 WO disclosed