Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141308 | 0.83 | KMT2A (0.46) | KMT2AHSD17B10GAACASP3ALDH1A1 | |
| SCHEMBL421448 | 0.79 | GRM2 (0.33) | GAAALDH1A1CYP1A2PPARGGRM2 | |
| SCHEMBL417860 | 0.79 | GRM2 (0.33) | GAAALDH1A1CYP1A2PPARGGRM2 | |
| SCHEMBL3283828 | 0.78 | CASP3 (0.41) | KMT2AHSD17B10GAACASP3ALDH1A1 | |
| SCHEMBL13515136 | 0.78 | HTT (0.42) | KMT2AHSD17B10GAACASP3ALDH1A1 | |
| SCHEMBL3284319 | 0.76 | CASP3 (0.40) | KMT2AHSD17B10GAACASP3ALDH1A1 | |
| SCHEMBL16812127 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP1A2PPARGGRM2SIRT2 | |
| SCHEMBL419843 | 0.73 | HTT (0.33) | — | |
| SCHEMBL418271 | 0.73 | HTT (0.33) | — | |
| SCHEMBL6314895 | 0.72 | KMT2A (0.49) | KMT2AHSD17B10GAACASP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461341-B1 | PROCESS FOR PREPARING A HETEROAROMATIC COMPOUND SUBSTITUTED WITH ONE OR MORE ETHER GROUPS | AGFA GEVAERT (BE) | 2010-01-27 | — | — | EP | disclosed |
| US-6734312-B2 | CONDENSING HYDROXY- GROUP OF A COMPOUND HAVING HETEROAROMATIC NUCLEUS, WITH AN ALCOHOL CONTAINING ONE OR MORE PRIMARY OR SECONDARY ALCOHOL GROUPS, OPTIONALLY USING THE REDOX COUPLE OF A TRIARYL- OR TRIALKYLPHOSPHINE AND AN AZODIOXO-COMPOUND | AGFA-GEVAERT (BE) | 2004-05-11 | — | — | US | disclosed |
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | AGFA-GEVAERT (BE) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | ADH1C, ADH1A, CYP2E1 | KMT2A 1445/4885HSD17B10 93/4885GAA 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.