SCHEMBL27238

SCHEMBL27238

[CH2]C(OC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
EPHX1 P07099 1/20 0.39
THRB P10828 1/20 0.39
CYP2D6 P10635 1/20 0.39
MC4R P32245 1/20 0.39
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
CA4 P22748 1/20 0.38
MIF P14174 2/20 0.37
TAAR1 Q96RJ0 2/20 0.36
HTR2A P28223 1/20 0.36
HRH1 P35367 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7327576 1.00 KMT2A (0.41) KMT2AEPHX1THRBCYP2D6MC4R
SCHEMBL9066760 0.86 PTGS2 (0.44) EPHX1
SCHEMBL10813004 0.77 CHRNA7 (0.41)
SCHEMBL6632699 0.75 CYP3A4 (0.43) KMT2ACYP2D6LMNA
SCHEMBL28835630 0.75 TDP1 (0.42) KMT2ATSHR
SCHEMBL16798345 0.75 CA1 (0.52) THRBCYP2D6TSHRLMNA
SCHEMBL4196376 0.75 AOC3 (0.44) CYP2D6TSHRHRH1LMNA
SCHEMBL28467958 0.75 MIF (0.39) CYP2D6DPP4F2TSHRMIF
SCHEMBL16798444 0.75 SLC6A4 (0.48) KMT2ATSHRLMNA
SCHEMBL6629617 0.73 CFTR (0.48) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688124-B1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-25 EP claimed
WO-2023177250-A1 NOVEL HETEROCYCLIC INHIBITOR FOR HISTONE DEACETYLASE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 숙명여자대학교산학협력단 2023-09-21 WO claimed
EP-3688124-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-08-05 EP claimed
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
CN-111386331-A Ester compound, lubricating oil composition containing same, and method for producing same 埃克森美孚化学专利公司 2020-07-07 CN claimed
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-04 US claimed
WO-2019067061-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-04-04 WO claimed
US-10071984-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2018-09-11 US claimed
US-9676770-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2017-06-13 US claimed
CN-101851238-B Substituted 8-heteroaryl xanthines ADENOSINE THERAPEUTICS LLC 2012-07-18 CN claimed
WO-2003099818-A1 SUBSTITUTED QUINAZOLINONE COMPOUNDS CHIRON CORPORATION (US) 2003-12-04 WO claimed
EP-0758320-A1 TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS Allelix Biopharmaceuticals Inc. (CA) 1997-02-19 EP claimed
WO-1995030655-A1 TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS ALLELIX BIOPHARMACEUTICALS INC. (CA) 1995-11-16 WO claimed
EP-0186028-B1 OPTICALLY ACTIVE NITRODIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES BAYER AG (DE) 1990-08-01 EP claimed
EP-0211584-A1 Antihypertensive agents AMERICAN HOME PRODUCTS CORPORATION (US) 1987-02-25 EP claimed
EP-0093010-B1 ALPHA-HYDROXYETHYLPHOSPHINATES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-06-11 EP claimed
EP-0026317-B1 OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1985-10-16 EP claimed
EP-0157415-A2 Pyrazolo[4,3-d] pyrimidine derivative process for its production antihyperlipidemic agent containing it, its intermediate, and process for the production of the intermediate NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-10-09 EP claimed
EP-0101023-A1 Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process BANYU PHARMACEUTICAL CO., LTD. (JP) 1984-02-22 EP claimed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10071984-B2 Histone demethylase inhibitors KDM1B, KDM1A, KDM3B KMT2A 40/4885EPHX1 1289/4885THRB 3279/4885
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same ELOVL1, NOTUM, ELOVL5 KMT2A 4001/4885EPHX1 384/4885THRB 4227/4885
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same ELOVL1, NOTUM, ELOVL5 KMT2A 4001/4885EPHX1 384/4885THRB 4227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.