Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27242575 | 0.89 | SCN10A (0.46) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL27242503 | 0.88 | SCN10A (0.46) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL27242598 | 0.85 | SCN10A (0.50) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL30895712 | 0.83 | MET (0.43) | — | |
| SCHEMBL24906473 | 0.82 | CA1 (0.48) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL27242584 | 0.80 | ROCK1 (0.49) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL27242479 | 0.79 | ALDH1A1 (0.44) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL30895664 | 0.77 | KDM4E (0.42) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL27242530 | 0.77 | PTGER4 (0.51) | SCN10ACA1CA2CA9CA12 | |
| SCHEMBL30895659 | 0.77 | IDH1 (0.49) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |