Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890471 | 0.87 | NR1H2 (0.41) | — | |
| SCHEMBL27244814 | 0.84 | L3MBTL1 (0.33) | AKR1B1MAPT | |
| SCHEMBL27245173 | 0.82 | OTUD7B (0.36) | — | |
| SCHEMBL27244767 | 0.78 | AKR1B1 (0.39) | AKR1B1 | |
| Hydrochloric Acid SCHEMBL27244995 | 0.77 | TDP1 (0.34) | TDP1AKR1B1BRD4 | |
| Hydrochloric Acid SCHEMBL30890534 | 0.77 | TDP1 (0.34) | TDP1AKR1B1BRD4 | |
| SCHEMBL27244758 | 0.75 | OTUD7B (0.38) | — | |
| SCHEMBL27244782 | 0.73 | SIRT2 (0.30) | — | |
| SCHEMBL27245195 | 0.73 | OTUD7B (0.37) | — | |
| SCHEMBL27245098 | 0.73 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | TDP1 2526/4885AKR1B1 3356/4885BRD4 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.