Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 0.81 |
| ▸ | ITPR1 | Q14643 | 5/20 | 0.81 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.81 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.77 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.70 |
| ▸ | AKT1 | P31749 | 1/20 | 0.70 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184816 | 0.95 | ITPR3 (0.77) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL1569348 | 0.95 | ITPR3 (0.86) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL381972 | 0.95 | ITPR3 (0.77) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL8775574 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9387601 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9094714 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL2044892 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL405897 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL8994052 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9091912 | 0.90 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635640-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | Biosynth AG (CH) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059583-A1 | NOVEL APPLICATIONS OF INDOLOINDOLE AND INDOLOQUINOLINE DYES | BIOSYNTH AG (CH) | 2012-05-10 | — | — | WO | disclosed |