SCHEMBL2044892

SCHEMBL2044892

O=P(O)(O)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 8/20 1.00
ITPR2 Q14571 4/20 1.00
ITPR1 Q14643 4/20 1.00
INPP5A Q14642 2/20 0.84
INPPL1 O15357 1/20 0.75
AKT1 P31749 1/20 0.75
SMPD1 P17405 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091859 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9093199 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9094714 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL2510044 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL8994052 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9091912 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL405897 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL8775574 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9387601 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL15067019 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180457-A1 SYNTHETIC GLYCEROPHOSPHOLIPIDS COMPRISING AT LEAST ONE REACTIVE FUNCTION, PROCESS FOR PREPARING SAME AND USES THEREOF IN DIFFERENT APPLICATIONS UNIVERSITE DE ROUEN-NORMANDIE (FR) 2023-09-28 WO claimed
US-20210106681-A1 ORGANICALLY MODIFIED MINERAL MICRO-PARTICLES, METHODS OF PREPARING THE SAME AND USES THEREOF CRODA INTERNATIONAL PLC (GB) 2021-04-15 US claimed
EP-3781517-A1 ORGANICALLY MODIFIED MINERAL MICRO-PARTICLES, METHODS OF PREPARING THE SAME AND USES THEREOF Croda International PLC (GB) 2021-02-24 EP claimed
WO-2019201710-A1 ORGANICALLY MODIFIED MINERAL MICRO-PARTICLES, METHODS OF PREPARING THE SAME AND USES THEREOF CRODA DENMARK A/S (DK) 2019-10-24 WO claimed
EP-3556728-A1 ORGANICALLY MODIFIED MINERAL MICRO-PARTICLES, METHODS OF PREPARING THE SAME AND USES THEREOF Croda Denmark A/S (SE) 2019-10-23 EP claimed
CN-101614970-B Photoresist cleaning agent composition ANJI MICROELECTRONICS CO LTD 2012-12-19 CN claimed
CN-101686986-A Cyclitols and derivatives thereof and their therapeutic use NORMOXYS INC 2010-03-31 CN claimed
CN-101614970-A A kind of photoresist cleansing composition ANJI MICROELECTRONICS CO LTD 2009-12-30 CN claimed
EP-2111226-A2 CYCLITOLS AND THEIR DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS Normoxys, Inc. (US) 2009-10-28 EP claimed
US-20080200437-A1 Polyphosphorylated inositol derivatives; allosteric effectors, cell signaling molecule analogs; hypoxia related diseases UNIVERSITE DE STRASBOURG (FR) 2008-08-21 US claimed
WO-2008082658-A2 CYCLITOLS AND THEIR DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS NORMOXYS, INC. (US) 2008-07-10 WO claimed
EP-4370667-A1 PHYTASE VARIANTS AB Enzymes Oy (FI) 2024-05-22 EP disclosed
EP-4370669-A1 PHYTASE VARIANTS AB Enzymes Oy (FI) 2024-05-22 EP disclosed
EP-4370670-A1 PHYTASE VARIANTS WITH IMPROVED STABILITY AND IP4 ACTIVITY AB Enzymes Oy (FI) 2024-05-22 EP disclosed
US-20240115595-A1 MATERIAL COMPOSITIONS AND METHODS OF USE IMPROVING RNA STABILITY TEAM MEDICAL, LLC (US) 2024-04-11 US disclosed
WO-1990002201-A1 METHOD AND KIT FOR DIAGNOSIS OF MALIGNANT HYPERPYREXIA THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1990-03-08 WO disclosed
US-4873355-A Process for regioselectively preparing phosphorylated inositols and other cyclitols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-10 US disclosed
US-4839466-A Insulin activity messengers THE ROCKEFELLER UNIVERSITY (US) 1989-06-13 US disclosed
EP-0245956-A2 Insulin activity messengers, their precursors and uses thereof ROCKEFELLER UNIVERSITY (US) 1987-11-19 EP disclosed
EP-0233403-A1 Photo-labile protecting agents and method MEDICAL RESEARCH COUNCIL (GB) 1987-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200437-A1 Polyphosphorylated inositol derivatives; allosteric effectors, cell signaling molecule analogs; hypoxia related diseases PPIP5K2, IP6K1, IP6K3 ITPR3 23/4885ITPR2 20/4885ITPR1 13/4885
US-20210106681-A1 ORGANICALLY MODIFIED MINERAL MICRO-PARTICLES, METHODS OF PREPARING THE SAME AND USES THEREOF ACP3, SOST, ALPP ITPR3 372/4885ITPR2 470/4885ITPR1 414/4885
US-20240115595-A1 MATERIAL COMPOSITIONS AND METHODS OF USE IMPROVING RNA STABILITY RBM22, HNRNPUL2, HNRNPUL1 ITPR3 3547/4885ITPR2 3622/4885ITPR1 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.